Macrophage polarization in metabolic disorders
نویسندگان
چکیده
منابع مشابه
Macrophage polarization in metabolic disorders: functions and regulation.
PURPOSE OF REVIEW To discuss recent findings on the role and regulation of macrophage polarization in obesity and atherosclerosis. RECENT FINDINGS Macrophages infiltrate the vascular wall during atherosclerosis and adipose tissue during obesity. At least two distinct subpopulations with different functions, the classically (M1) and the alternatively (M2) activated macrophages, have been found...
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Studying the metabolism of immune cells in recent years has emphasized the tight link existing between the metabolic state and the phenotype of these cells. Macrophages in particular are a good example of this phenomenon. Whether the macrophage obtains its energy through glycolysis or through oxidative metabolism can give rise to different phenotypes. Classically activated or M1 macrophages are...
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ژورنال
عنوان ژورنال: Current Opinion in Lipidology
سال: 2011
ISSN: 0957-9672
DOI: 10.1097/mol.0b013e32834a77b4